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[摘要]
目的 分析急性心肌梗死(AMI)合并心源性休克(CS)患者主动脉内球囊反博(IABP)术辅助治疗后主要终点事件的相关影响因素。方法 将我院125例AMI合并CS患者(2019年8月~2021年5月)作为研究对象,收集其临床资料(性别、年龄、治疗方法、合并症等),行Logistic回归分析,以了解AMI合并CS患者IABP术辅助治疗后主要终点事件的相关影响因素。结果 125例AMI合并CS患者IABP术辅助治疗后存活75例,存活率为60.00%(75/120),死亡50例,死亡率为40.00%(50/125);存活组、病死组的年龄、吸烟、伴有高血压、伴有糖尿病、伴有脑梗死、前壁梗死、冠脉病变支数多、IABP治疗后并发心排量不足、IABP治疗后并发肺部感染、PCI术后TIMI血流分级Ⅱ级、平均动脉压、TC、FBG、BUN水平对比,差异具有统计学意义(P<0.05);Logistic多元回归方程分析发现,年龄≥75岁、合并糖尿病、冠状动脉病变支数多、术后心肌梗死溶栓试验(TIMI)血流分级为Ⅱ级、IABP并发心排量不足为AMI合并CS患者IABP术辅助治疗后主要终点事件的危险因素(P<0.05)。结论 影响AMI合并CS患者IABP术辅助治疗后主要终点事件发生情况的因素较多,年龄、合并糖尿病、冠状动脉病变支数、术后TIMI血流分级、IABP并发症等均可引起不良预后,对此,临床应针对高危因素进行积极干预。
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[Abstract]
Objective To analyze the related influencing factors of the primary end point of patients with acute myocardial infarction (AMI) combined with cardiogenic shock (CS) after adjuvant intra-aortic balloon return (IABP) surgery. Methods 125 patients with AMI and CS in our hospital (from August 2019 to May 2021) were taken as the research objects, and their clinical data (gender, age, treatment methods, comorbidities, etc.) were collected, and Logistic regression analysis was performed to understand AMI Related influencing factors of the primary end point of patients with CS after IABP adjuvant therapy. Results 125 AMI patients with CS patients survived after IABP adjuvant therapy, the survival rate was 60.00% (75/120), 50 cases died, and the mortality rate was 40.00% (50/125); Smoking, with hypertension, with diabetes, with cerebral infarction, anterior wall infarction, more coronary artery disease, insufficient cardiac output after IABP treatment, pulmonary infection after IABP treatment, TIMI blood flow after PCI The difference in grade Ⅱ, mean arterial pressure, TC, FBG, and BUN levels was statistically significant (P<0.05); Logistic multiple regression analysis found that patients with age ≥75 years old, diabetes mellitus, more coronary artery disease, postoperative myocardial infarction thrombolytic test (TIMI) blood flow classification of Ⅱ, IABP and insufficient cardiac output are AMI patients with CS The risk factors of the primary endpoint after IABP adjuvant treatment (P<0.05). Conclusion There are many factors that affect the occurrence of the primary endpoint of AMI patients with CS after IABP adjuvant treatment. Age, diabetes, coronary artery disease, postoperative TIMI blood flow grade, IABP complications, etc. can all cause poor prognosis. Therefore, clinical interventions should be made for high-risk factors.
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